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Product Details
Melatonin is not the major regulator of normal sleep patterns, but undoubtedly has a major effect. One topic that has generated a large amount of interest using melatonin alone, or in combination with phototherapy, is to treat sleep disorders. There is some indication that melatonin levels are lower in elderly insomniacs relative to age-matched noninsomniacs, and melatonin therapy in such cases appears modestly beneficial in correcting the problem. Another sleep disorder is seen in shift workers, who often find it difficult to adjust working at night and sleeping during the day; the utility of melatonin therapy to alleviate this problem is equivocal and appears not to be as effective as phototherapy. Still another condition involving disruption of circadian rhythms is jet lag; in this case, it has repeatedly been demonstrated that taking melatonin close to the target bedtime of the destination can alleviate symptoms—melatonin has the greatest beneficial effect when jet lag is predicted to be worst (e.g. crossing many time zones). In various species including humans, administration of melatonin has been shown to decrease motor activity, induce fatigue, and lower body temperature, particularly at high doses. The effect on body temperature may play a significant role in melatonin’s ability to entrain sleep-wake cycles, as in patients with jet lag.
Suggested Use
Adults:
Take ½–2 tablets daily or as directed by your health-care practitioner.
Take once a day, at or before bedtime.
- For jet lag:
Take once a day at bedtime after darkness has fallen, while travelling and at destination, until adaptation to the new daily pattern, on occasional short-term use.
- For sleep restriction/altered sleep schedule; for delayed sleep phase disorder; and to restore sleep-wake cycle:
Consult a health-care practitioner for use beyond 4 weeks.
Cautions
Do not drive or use machinery for 5 hours after taking melatonin.